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Fatness QTL on chicken chromosome 5 and interaction with sex

Genetics Selection Evolution volume 38, Article number: 297 (2006) Cite this article

Abstract

Quantitative trait loci (QTL) affecting fatness in male chickens were previously identified on chromosome 5 (GGA5) in a three-generation design derived from two experimental chicken lines divergently selected for abdominal fat weight. A new design, established from the same pure lines, produced 407 F2 progenies (males and females) from 4 F1-sire families. Body weight and abdominal fat were measured on the F2 at 9 wk of age. In each sire family, selective genotyping was carried out for 48 extreme individuals for abdominal fat using seven microsatellite markers from GGA5. QTL analyses confirmed the presence of QTL for fatness on GGA5 and identified a QTL by sex interaction. By crossing one F1 sire heterozygous at the QTL with lean line dams, three recombinant backcross 1 (BC1) males were produced and their QTL genotypes were assessed in backcross 2 (BC2) progenies. These results confirmed the QTL by sex interaction identified in the F2 generation and they allow mapping of the female QTL to less than 8 Mb at the distal part of the GGA5. They also indicate that fat QTL alleles were segregating in both fat and lean lines.

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Authors and Affiliations

  1. UMR Inra-Agrocampus Génétique animale, 35042, Rennes, France

    Behnam Abasht, Sandrine Lagarrigue, Pascale Le Roy, Olivier Demeure & Madeleine Douaire

  2. Laboratoire de génétique cellulaire, Inra, 31326, Auzeville, France

    Frédérique Pitel, Florence Vignoles & Alain Vignal

  3. Station de recherches avicoles, Inra, 37380, Nouzilly, France

    Elisabeth Le Bihan-Duval & Jean Simon

  4. SGQA, Inra, 78352, Jouy en Josas, France

    Pascale Le Roy & Larry Cogburn

  5. Department of Animal and Food Sciences, University of Delaware, Newark, DE, 19717, USA

    Sammy Aggrey

  6. University of Georgia, Athens, GA, 30602, USA

    Madeleine Douaire

Authors
  1. Behnam Abasht
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  2. Frédérique Pitel
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  3. Sandrine Lagarrigue
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  4. Elisabeth Le Bihan-Duval
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  5. Pascale Le Roy
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  6. Olivier Demeure
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  7. Florence Vignoles
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  8. Jean Simon
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  9. Larry Cogburn
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  10. Sammy Aggrey
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  11. Alain Vignal
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  12. Madeleine Douaire
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Corresponding author

Correspondence to Madeleine Douaire.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Abasht, B., Pitel, F., Lagarrigue, S. et al. Fatness QTL on chicken chromosome 5 and interaction with sex. Genet Sel Evol 38, 297 (2006). https://doi.org/10.1186/1297-9686-38-3-297

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  • DOI: https://doi.org/10.1186/1297-9686-38-3-297

Keywords

Genetics Selection Evolution

ISSN: 1297-9686