Large-scale association study for structural soundness and leg locomotion traits in the pig

doi:10.1186/1297-9686-41-14

Genetics Selection Evolution

Volume 41

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Onteru SK
Mote BE
Serenius T
Stalder KJ
Rothschild MF

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Mote BE
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Rothschild MF
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Large-scale association study for structural soundness and leg locomotion traits in the pig

Bin Fan¹^,2 , Suneel K Onteru¹ , Benny E Mote¹ , Timo Serenius¹ , Kenneth J Stalder¹ and Max F Rothschild¹

¹Department of Animal Science and Center for Integrated Animal Genomics, Iowa State University, Ames, IA 50011, USA

²Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, Ministry of Education & College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070, PR China

author email corresponding author email

Genetics Selection Evolution 2009, 41:14doi:10.1186/1297-9686-41-14


Published:	21 January 2009

Additional files

Additional File 1:

Appendix One. The criteria for the scoring of the analyzed traits in the study.

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Table Two. The characteristics of the analyzed SNPs (SNPs were sorted by their chromosomal locations).

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Appendix Two. The phenotypic correlations between the 17 analyzed traits of body conformation, feet and leg structure and overall leg action.

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Appendix Three. The eigenvalues and eigenvectors of principal component (PC) analysis on the 17 analyzed traits.

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Appendix Four. Association analyses results of single SNP markers with body conformation, feet and leg structure traits and principal factors in two commercially available breeding female lines (The x-axis indicates individual SNPs distributed along with pig chromosomes and y-axis indicates -log (P-value). SNPs with P < 0.001 and being under the 20% threshold of FDR are labeled. a) overall leg action; b) body depth; c) body length; d) body width; e) hip structure; f) rib shape; g) top line; h) front leg buck knee; i) front foot size; j) front pastern posture; k) front leg turned in/out; l) front uneven toes; m) rear foot size; n) rear pastern posture; o) rear leg turned in/out; p) rear uneven toes; q) rear weak leg; r) PC1 of body conformation traits; s) PC2 of body conformation traits; t) PC1 of feet and leg structure; u) PC2 of feet and leg structure).

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Table Three. The list of significant SNPs for the 17 analyzed traits of body conformation, feet and leg structure and overall leg action.

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Table Four. The association analyses between putative haplotypes of CALCR and COL1A2 in SSC9, and the individual traits as well as principal components.

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