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An accurate formula to calculate exclusion power of marker sets in parentage assignment

Marc Vandeputte

Author Affiliations

INRA, UMR1313 Animal Genetics and Integrative Biology, Jouy-en-Josas, 78350, France

Ifremer, UMR110 INTREPID, Palavas-les-Flots, 34250, France

Genetics Selection Evolution 2012, 44:36  doi:10.1186/1297-9686-44-36

Published: 3 December 2012

Abstract

In studies on parentage assignment with both parents unknown, the exclusion power of a marker set is generally computed under the hypothesis that the potential families tested are independent and unrelated samples. This tends to produce overly optimistic exclusion power estimates. In this work, we have developed a new formula that gives almost unbiased results at the population level.